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There are several matches for 'dITP/XTP pyrophosphatase'.
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8388 matches
showing page 1 of 420
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organism
protein
1)
Escherichia coli K12
rdgB - dITP/XTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Can also efficiently hydrolyze 2'- deoxy-N-6-hydroxylaminopurine triphosphate (dHAPTP). Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. To a much lesser extent, is als [...]
[a.k.a. b2954, AAC75991.1, 947429,
DITP/XTP pyrophosphatase
,
dITP/XTP pyrophosphatase
, ...]
2)
Homo sapiens
ITPA - Inosine triphosphate
pyrophosphatase
;
Pyrophosphatase
that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (
dITP
) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (
XTP
) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.
[a.k.a. NM_181493, AF219116, AAK21848.1]
3)
Mus musculus
Itpa - Inosine triphosphate
pyrophosphatase
;
Pyrophosphatase
that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (
dITP
) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (
XTP
) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. BAE32246.1, BC026508, Itpa-204]
4)
Drosophila melanogaster
CG8891 - Inosine triphosphate
pyrophosphatase
;
Pyrophosphatase
that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (
dITP
) or xanthosine 5'-triphosphate (
XTP
) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. FBgn0031663, CG8891-PA, NP_608890.1]
5)
Caenorhabditis elegans
hap-1 - Inosine triphosphate
pyrophosphatase
;
Pyrophosphatase
that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (
dITP
) or xanthosine 5'-triphosphate (
XTP
) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. ZC395.7, Q9GYG4, CELE_ZC395.7]
6)
Saccharomyces cerevisiae
HAM1 - Inosine triphosphate
pyrophosphatase
; Nucleoside triphosphate pyrophosphohydrolase; active against various substrates including ITP,
dITP
and
XTP
; mediates exclusion of non canonical purines, pyrimidines from dNTP pools; functions with YJL055W to mediate resistance to 5-FU; specifically reduces the incorporation of 5-FU into RNA without affecting uptake or incorporation of uracil into RNA; protein abundance increases in response to DNA replication stress; yeast HAM1 can complement knockdown of human homolog ITPA.
[a.k.a. YJR069C, NP_012603.1, CAA89597.1]
7)
Abiotrophia defectiva
ESK66547.1 - Non-canonical purine NTP
pyrophosphatase
, RdgB/HAM1 family;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. GCWU000182_000237, W1Q5P9_ABIDE, XTP/dITP diphosphatase,
dITP/XTP pyrophosphatase
]
8)
Absiella dolichum
rdgB - Non-canonical purine NTP
pyrophosphatase
, RdgB/HAM1 family;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. EUBDOL_01935, EDP10677.1, A8RDG4_9FIRM,
dITP/XTP pyrophosphatase
]
9)
Acaryochloris marina
ham1 - Non-canonical purine NTP
pyrophosphatase
, RdgB/HAM1 family;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. ABW29645.1, AM1_4672, NC_009925.1,
dITP/XTP pyrophosphatase
]
10)
Accumulibacter aalborgensis
yggV - dITP/XTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. ACCAA_520015, SBT08079.1, Non-standard purine NTP pyrophosphatase,
dITP/XTP pyrophosphatase
]
11)
Accumulibacter phosphatis
ACV34275.1 - Non-canonical purine NTP
pyrophosphatase
, rdgB/HAM1 family;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. CAP2UW1_0938, NC_013194.1, C7RPN2_ACCPU,
dITP/XTP pyrophosphatase
]
12)
Accumulibacter sp. 6626
OJW48867.1 - Non-canonical purine NTP
pyrophosphatase
, RdgB/HAM1 family;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. BGO63_05795, A0A1Q3VQP4, OJW48867,
dITP/XTP pyrophosphatase
]
13)
Accumulibacter sp. BA93
AW11_01445 - Non-canonical purine NTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. EXI89578.1, Non-standard purine NTP pyrophosphatase, Nucleoside-triphosphate diphosphatase,
dITP/XTP pyrophosphatase
]
14)
Accumulibacter sp. BA94
rdgB - dITP/XTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. AW12_00710, EXI92251.1, Non-standard purine NTP pyrophosphatase,
dITP/XTP pyrophosphatase
]
15)
Accumulibacter sp. SK01
KFB67276.1 - Non-canonical purine NTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. CAPSK01_003394, A0A084XXT2, A0A084XXT2_9PROT,
dITP/XTP pyrophosphatase
]
16)
Accumulibacter sp. SK02
KFB77742.1 - Non-canonical purine NTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. AW06_001117, KFB77742, Non-standard purine NTP pyrophosphatase,
dITP/XTP pyrophosphatase
]
17)
Accumulibacter sp. SK11
AW07_00264 - Non-canonical purine NTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. EXI76865.1, EXI76865, A0A011PJ33_9PROT,
dITP/XTP pyrophosphatase
]
18)
Accumulibacter sp. SK12
rdgB - dITP/XTP
pyrophosphatase
;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. AW08_00494, EXI69286.1, A0A011N317,
dITP/XTP pyrophosphatase
]
19)
Acetanaerobacterium elongatum
SDN71096.1 - XTP/dITP diphosphohydrolase;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. SAMN05192585_12923, A0A1H0DM19_9FIRM, XTP/dITP diphosphohydrolase,
dITP/XTP pyrophosphatase
]
20)
Acetitomaculum ruminis
SFA83676.1 - XTP/dITP diphosphohydrolase;
Pyrophosphatase
that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides
XTP
(xanthosine triphosphate),
dITP
(deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
[a.k.a. SAMN05216249_10383, A0A1I0W6Y6_9FIRM, XTP/dITP diphosphohydrolase,
dITP/XTP pyrophosphatase
]
8388 matches
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